Adipotide / FTPP — illustrative photo of a kit of 10 vials — Illustrative packaging. Supplied materials and packaging vary by order.

Metabolic research · Research peptides

Adipotide / FTPP

Adipotide / FTPP is listed as a research peptides material for qualified research and analytical procurement workflows.

Every lot ships with its COA — HPLC purity + MS identity
Purity specification ≥ 99.0%
From 1 kit (10 vials) per SKU
Written quote by email or WhatsApp

This entry is on the controlled SKU list; the first reply confirms its technical scope before procurement.

Specification

$195.50 / kit of 10 vials

$19.55 per vial · line total $195.50

kit · 10 vials

Need another spec, a larger fill or custom labelling?

Reference prices · Adipotide / FTPP 5 mg
Kits on your quote list	Price / kit
Retail · 1–4 kits	$195.50
Wholesale · 5–19 kits (−20%)	$156.40
20+ kits	Ask for a quote

Kits count across your whole quote list, so different products add up. Pricing FAQ

Reference prices in USD, per kit of 10 vials. The final price is the one on your written quote. Need another currency? Your sales representative can quote it.

Specifications

Adipotide / FTPP parameters

CAS number	859216-15-2
Molecular formula	C111H206N36O28S2
Molecular weight	2557.2 g/mol
Sequence	CKGGRAKDCGGKLAKLAKKLAKLAK
PubChem CID	163360068
Purity specification	≥ 99.0% (HPLC)
Appearance	White to off-white lyophilized powder
Specifications	2 mg, 5 mg, 10 mg
Kit	10 vials per kit · minimum 1 kit per SKU
Storage	Storage and handling requirements are configuration- and lot-specific; request the applicable documentation before ordering.

Specifications and reference prices
SKU	Content	Price / kit	Per vial
`ADIP2`	2 mg	On request	—
`ADIP5`	5 mg	$195.50	$19.55
`ADIP10`	10 mg	$296.70	$29.67

Another format

Adipotide / FTPP in a nasal spray bottle

Strengths: 2 mg · 5 mg
Fill: 10 mL or 20 mL
At least: 10 bottles of one strength and size
Dispatched from: US stock, to US addresses

Nasal sprays are quoted by our sales team, separately from the kits on your quote list.

Black 10 mL nasal spray bottle with a clear dust cap — Spray bottle, 10 mL

Test results for every lot

Each lot of Adipotide / FTPP has its own certificate of analysis with HPLC purity and mass-spectrometry (MS) identity. Other tests — water content, counter-ion, endotoxin — are available on request and listed on the COA when tested.

Batch COAs 3

Batch COA, lot release

Adipotide / FTPP

2 mg

HPLC purity · MS identity

Batch COA, lot release

Adipotide / FTPP

5 mg

HPLC purity · MS identity

Batch COA, lot release

Adipotide / FTPP

10 mg

HPLC purity · MS identity

Previews show the first page only, at a resolution where small print cannot be read; numbers, dates, names and signatures are covered. The full, clear copy comes from our sales team.

COA of the batch you receive: ask our sales team.

Independent test fails? Full refund. How the refund works

How to read a COA →

Research background

About Adipotide / FTPP

Adipotide (also designated FTPP, FTTP, or prohibitin-targeting peptide 1 in the published literature) is a research peptidomimetic with a two-domain structure: a cyclic CKGGRAKDC homing motif that recognizes prohibitin on the endothelium of white-adipose-tissue blood vessels, fused via a GG linker to a D(KLAKLAK)2 pro-apoptotic sequence that disrupts mitochondrial membranes once delivered to its target tissue. The molecule was developed by Renata Pasqualini and Wadih Arap at the University of Texas MD Anderson Cancer Center as a vascular-targeting approach to obesity research, the homing motif targets the adipose-vasculature endothelium, and the apoptotic domain then triggers selective destruction of the adipose-supporting blood vessels in primate obesity models.

Medabol supplies Adipotide as a lyophilized powder with a ≥99.0% HPLC specification. Ask sales for the batch COA matched to the offered lot; it records the identity and purity work actually completed. If the buyer's written procedure requires sequence-level or disulfide-state evidence, agree the method, reporting format, timing, and cost before quotation.

Selected literature

Kolonin MG, Saha PK, Chan L, Pasqualini R, Arap W. Reversal of obesity by targeted ablation of adipose tissue. Nat Med. 2004;10(6):625-632.
Barnhart KF, Christianson DR, Hanley PW, et al. A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys. Sci Transl Med. 2011;3(108):108ra112.
Staquicini FI, Cardó-Vila M, Kolonin MG, et al. Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients. Proc Natl Acad Sci U S A. 2011;108(46):18637-18642.
Salameh A, Daquinag AC, Staquicini DI, et al. Prohibitin/annexin 2 interaction regulates fatty acid transport in adipose tissue. JCI Insight. 2016;1(10):e86351.
Fang Y, Kaszuba T, Imoukhuede PI. Systems biology will direct vascular-targeted therapy for obesity. Front Physiol. 2020;11:831.

For laboratory research use. This page describes published research and the material we supply; it is not medical advice.

Adipotide / FTPP FAQ

What's the design rationale for Adipotide's two-domain structure?

Adipotide combines a vascular-homing motif (the cyclic CKGGRAKDC peptide) with a pro-apoptotic effector (D(KLAKLAK)2) connected by a GG linker. The homing motif recognizes prohibitin displayed on the endothelium of blood vessels supplying white adipose tissue, a tissue-specific signature that distinguishes adipose vasculature from most other vascular beds. Once the homing peptide binds, the D(KLAKLAK)2 domain (a synthetic mitochondrial-membrane-disrupting amphipathic peptide built from D-amino acids for protease resistance) is delivered into the target endothelial cells where it triggers apoptosis. The vascular-targeting approach was novel for obesity research at the time of publication, destroying the support vasculature of adipose tissue rather than directly targeting adipocytes.

Why is sequence verification by LC-MS/MS recommended for Adipotide?

Adipotide's construct combines several features that complicate identity confirmation: (1) the N-terminal CKGGRAKDC is disulfide-cyclized (Cys1 to Cys9), creating a cyclic mass distinct from the linear precursor; (2) the central GG linker is straightforward but at the boundary between the two functional domains; and (3) the D(KLAKLAK)2 effector uses D-amino acids that don't change mass but do change biological behavior. Mass-spec alone confirms the overall mass but can't distinguish between, say, a non-cyclized linear precursor and the intended disulfide-cyclized product, nor can it distinguish L-amino-acid from D-amino-acid by mass. LC-MS/MS sequence verification covering both domains is the only test that confirms the construct as supplied matches the intended design.

How to order

Ordering Adipotide / FTPP from Medabol

Kit and minimum: Adipotide / FTPP is sold by the kit: 10 vials of one specification (2 mg, 5 mg and 10 mg). The minimum is 1 kit per SKU, so an individual buyer can order a single kit and a lab can order many.
Price: Reference prices are listed per kit above, from $195.50. The kits of your whole quote list count together — 5–19 kits are 20% off every kit, and from 20 kits our sales team quotes the price — so Adipotide / FTPP adds up with anything else you order; your written quote has the final price.
Documents: Every lot has its own COA with HPLC purity and MS identity; the order ships with the certificate of its lot, and our sales team sends it before you order if you ask.
Shipping: Orders ship from China by international express courier. Shipping from $80 per order; the written quote confirms the exact charge for your destination.
Payment: Nothing is paid on this website. After you send your quote list, a sales representative confirms the amount and shipping on WhatsApp or by email and tells you in that chat how to pay.
Research goal: Listed under Metabolic research — Incretin and amylin analogues and energy-balance compounds.

Questions first?

Ask about Adipotide / FTPP.

Quantities, documents, timing or a spec that is not listed — the reply comes from a sales representative.

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Adipotide / FTPP

Adipotide / FTPP parameters

Adipotide / FTPP in a nasal spray bottle

Test results for every lot

Batch COAs 3

Adipotide / FTPP

Adipotide / FTPP

Adipotide / FTPP

About Adipotide / FTPP

Selected literature

Adipotide / FTPP FAQ

Ordering Adipotide / FTPP from Medabol

Ask about Adipotide / FTPP.

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